In this YouTube video, created by Southwest Center for Microsystems Education (SCME), viewers are introduced to the concept of DNA microarrays including what they are and how they are used today. DNA microarrays are used in a variety of fields including medicine, agriculture, and toxicology and have led to important discoveries in disease research. DNA microarrays look at our genes and examine whether or not certain genes are present, and help us to compare DNA from different people or species. A short review of genes is included to provide a greater prospective for the functionality of microarrays. This is the first in a series of presentations on DNA microarrays. Supporting materials can be downloaded from the SCME website.