This lesson, presented by the National Nanotechnology Infrastructure Network, covers self-assembly of molecules. Two activity are contained in this lesson. The first is "a hands-on modeling activity designed to introduce students to the area of nanotechnology and give them a basic understanding of how researchers build very small devices by the self-assembly of molecules." The second activity follows up on the first and gives "the students a chance to practice and demonstrate what they have learned." Two Teacher Preparation Guides and Two Student Guides are included.