Microbial Factor-Mediated Development in a Host-Bacterial Mutualism

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Title:

Microbial Factor-Mediated Development in a Host-Bacterial Mutualism

Url:

https://www.science.org/doi/10.1126/science.1102218

Publisher:

Science Magazine

Description: This Science Magazine scholarly article explores the function of bacterial signal molecule Tracheal cytotoxin (TCT) in the mutualistic symbiosis between the bacterium Vibrio fischeri and the squid Euprymna scolopes. TCT is the factor responsible for the extensive tissue damage characteristic of whooping cough and gonorrhea infections in humans, however this article demonstrates that it triggers tissue development in the squid host. These findings show that host interpretation of such bacterial signal molecules is context-dependent. Such differences in interpretation can lead to either inflammation and disease or to the establishment of a mutually beneficial animal-microbe association.

LC Classification:

Science -- Microbiology -- Addresses, essays, lectures
Science -- Natural history. Biology -- Biology (General) -- Ecology -- Special aspects of the subject as a whole, A-Z -- Molecular ecology
Science -- Natural history. Biology -- Biology (General) -- Ecology -- Symbiosis -- Mutualism
Science -- Natural history. Biology -- Biology (General) -- Evolution

GEM Subject:

Science -- Biology
Science -- Technology
Science -- Ecology

Key Concept:

Biology -- Molecules
Ecology -- Mutualism

Resource Type:

Reference Material

Format:

Document -- PDF
Document -- HTML

Audience:

Educator
Learner

Education Level:

High School
Higher Education
Higher Education -- Undergraduate (Lower Division)
Higher Education -- Undergraduate (Upper Division)
Higher Education -- Technical Education (Upper Division)
Higher Education -- Technical Education (Lower Division)
Vocational/Professional Development Education

Language:

English

Rights:

American Association for the Advancement of Science

Access Rights:

Free access

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Source:

Microbial Life

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