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View Resource The Busy Researcher's Guide to Biomolecule Chromatography

The Busy Researcher's Guide to Biomolecule Chromatography is a book (available in PDF format) focused on the vendor's (PerSeptive Biosystems) products (perfusion-based chromatography) with an eye toward their application in bioanalysis. The book is a nicely written and practical introduction to chromatography suitable for use with undergraduates. The last several chapters define the basics of...

View Resource Chromatography Theory

This site contains standard definitions related to chromatography similar to treatments found in analytical chemistry textbooks. It introduces the beginning student to Liquid Chromatography concepts relevant to biochemistry and includes a good example of choosing a mobile phase pH for a protein separation based on ion exchange.

View Resource Chromatography Theory and Modes

This site is an introductory lecture in outline form about chromatography. It appears directed toward biochemical separations. The coverage is broad but not deep. Discussions of counter-current separations, gel permeation, and ion exchange are accompanied by some mention of partition, paper, and gas chromatography. Useful illustrations are also included.

View Resource Affinity Chromatography

Using exposition, graphics, and commercial videos, this module teaches the theory and application of affinity chromatography in the characterization of proteins, nucleic acids, and other biochemical/biomedical systems. Problems and application examples support the tutorial material.

View Resource Biosensors, Nanosensors and Biochips: Frontiers in Environmental and Medical Diagnostics

Technologies developed at Oak Ridge National Laboratory include: 1) use of nanoprobes based on plasmon-resonance (which is defined) to enhance surface Raman scattering and fluorescence; 2) an optical neurosensor based on a 40 nm fiber optical tip; and 3) a multifunctional biochip capable of DNA and other protein-based bioassays. The article is available for download in PDF format with several...

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