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View Resource Alkaliphiles: Applications of Their Products for Biotechnology

This 16-page in-depth review article details the biotechnological applications of alkaliphiles. It begins by discussing the definition and history of alkaliphiles, and then analyzes their distribution and isolation. The article also reviews special physiological features of alkaliphiles, physical maps of chromosomal DNAs of alkaliphilic Bacillus strains, alkaline enzymes, metabolites produced by...

View Resource Disease Epidemic - ELISA Technique

From the University of California, Davis, Partnership for Plant Genomics Education, this biotechnology laboratory is a two-day activity using the ELISA assay, a "test that uses the immune system to detect disease," to study the epidemiology of a hypothetical small scale epidemic. The lesson gives the objectives, materials, necessary background information, advanced preparation notes, teacher...

View Resource An Adventure in Stereochemistry

This case study considers the problems that would arise if one were to cross over into a mirror-image environment. The case looks into the lock-and-key theory of enzyme action. This material would be most useful in biology, organic chemistry or biochemistry courses. The case study and teaching notes may be downloaded in PDF format. The site also includes a section for instructor feedback where...

View Resource Bioprospecting for Cellulose-Degrading Microbes

This high school-college level activity screens for cellulase-producing microbes from environmental samples of the students' choice. Students prepare samples, isolate them on selective media, and screen for cellulase activity. Two methods are provided, one focusing on isolation of pure microbial strains, the other focusing on finding symbiotic communities of microbes. Click on the Bioprospecting...

View Resource Drug Design: Protein Kinases

In this activity, by the Concord Consortium's Molecular Literacy project, students "review protein structure and hydrophilic/phobic interactions, and then study kinases, small proteins that regulate numerous cell processes." The activity itself is a java-based interactive resource built upon the free, open source Molecular Workbench software. In the activity, students are allowed to explore at...

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